Description

5-Methoxybenzofuran-2-Carbonyl Chloride is a versatile and highly reactive organic intermediate, specifically an acid chloride derivative of the benzofuran class. Its core value proposition lies in its role as a key building block for synthesizing more complex molecules, enabling efficient carbon-carbon and carbon-heteroatom bond formation. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to construct novel active ingredients and fine chemicals. The material is supplied to exacting standards to ensure reliable performance in sensitive synthetic applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the benzofuran scaffold's bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed to create specialized ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Fluorescent Probe and Dye Synthesis: Acts as a starting material for constructing benzofuran-based fluorophores used in bioimaging and sensors.
• Custom Synthesis and Contract Manufacturing: A key reagent for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	5-Methoxybenzofuran-2-Carbonyl Chloride
CAS No.	68898-11-3
Molecular Formula	C10H7ClO3
Molecular Weight	210.61 g/mol
Synonyms	5-Methoxy-2-benzofurancarbonyl chloride; 5-Methoxybenzofuran-2-carboxylic acid chloride; 2-Benzofurancarbonyl chloride, 5-methoxy-; 5-Methoxy-2-benzofuranyl carbonyl chloride; 5-Methoxy-2-benzofuroyl chloride; 5-Methoxycoumarone-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Methoxybenzofuran-2-Carbonyl Chloride is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards and customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.