Description

8-Amino-3-D-ribofuranosyl-1,2,4-triazolo(4,3-a)pyrazine is a high-purity nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound matters as a critical intermediate for the synthesis of novel antiviral and anticancer agents, particularly those targeting nucleoside metabolic pathways. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors focused on developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to purine and nucleoside metabolism.
• Antiviral Agent Development: Serves as a core scaffold for creating compounds that mimic natural nucleosides to disrupt viral replication.
• Oncology Research: Investigated for the development of chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Fine Chemical Synthesis: Employed in custom synthesis and the production of specialized, high-value chemical entities for research markets.
• Academic Research: Utilized in university and institutional labs for studying the structure-activity relationships of modified nucleosides.

Basic Information

Product Name	8-Amino-3-D-ribofuranosyl-1,2,4-triazolo(4,3-a)pyrazine
CAS No.	68797-11-5
Molecular Formula	C10H12N6O4
Molecular Weight	280.24 g/mol
Synonyms	8-Amino-3-β-D-ribofuranosyl[1,2,4]triazolo[4,3-a]pyrazine; 8-Amino-3-(β-D-ribofuranosyl)-1,2,4-triazolo[4,3-a]pyrazine; 8-Amino-3-(β-D-ribofuranosyl)-s-triazolo[4,3-a]pyrazine; 8-Amino-3-ribofuranosyl-1,2,4-triazolo[4,3-a]pyrazine; 8-Amino-3-β-D-ribofuranosyl-s-triazolo[4,3-a]pyrazine; 8-Amino-3-(β-D-ribofuranosyl)-v-triazolo[4,3-a]pyrazine; Nucleoside analog 68797-11-5; 1,2,4-Triazolo[4,3-a]pyrazine, 8-amino-3-β-D-ribofuranosyl-
EINECS	Contact for details

Quality Control

Our 8-Amino-3-D-ribofuranosyl-1,2,4-triazolo(4,3-a)pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.