Description

4H-Pyrimido[1,2-B]Pyridazine-3-Carbonyl Chloride, 4-Oxo- (9Ci) is a high-value, reactive chemical intermediate belonging to the fused pyrimidine-pyridazine class. This compound is critical for synthetic chemists as it serves as a versatile building block for constructing complex heterocyclic scaffolds with potential biological activity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

This specialized intermediate is designed for advanced synthetic applications where precise molecular construction is paramount.

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, or oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides with unique modes of action.
• Chemical Biology Probe Synthesis: Employed to create tool compounds for studying biological pathways and protein function.
• Material Science Precursor: Potential starting material for the synthesis of organic electronic materials or ligands for catalytic systems.
• Contract Research & Development (CRO): Supplied to research organizations engaged in custom synthesis and library generation for client projects.

Basic Information

Product Name	4H-Pyrimido[1,2-B]Pyridazine-3-Carbonyl Chloride, 4-Oxo- (9Ci)
CAS No.	68786-53-8
Molecular Formula	C8H4ClN3O2
Molecular Weight	209.59 g/mol
Synonyms	4-Oxo-4H-pyrimido[1,2-b]pyridazine-3-carbonyl chloride; 4H-Pyrimido[1,2-b]pyridazine-3-carbonyl chloride, 4-oxo-; 4-Oxopyrimido[1,2-b]pyridazine-3-carbonyl chloride; Pyrimido[1,2-b]pyridazine-3-carbonyl chloride, 4-oxo-4H-; 68786-53-8; 4H-Pyrimido[1,2-b]pyridazine-4-one-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4H-Pyrimido[1,2-B]Pyridazine-3-Carbonyl Chloride, 4-Oxo- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.