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(3A,5B,7B)-7-Hydroxy-3-(Sulfooxy)-Cholan-24-Oic Acid CAS NO 68780-73-4


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CAS No.:68780-73-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(3A,5B,7B)-7-Hydroxy-3-(Sulfooxy)-Cholan-24-Oic Acid is a sulfated bile acid derivative, a key intermediate in the synthesis of more complex steroid-based compounds. Its value lies in its specific stereochemistry and functional groups, which make it a crucial building block for pharmaceutical research and development. This compound is primarily needed by manufacturers and research institutions in the life sciences sector focusing on hepatobiliary therapeutics, metabolic studies, and advanced chemical synthesis.

Application

  • Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel therapeutic agents targeting liver and metabolic diseases.
  • Biochemical Research: Used as a reference standard or probe in studies of bile acid metabolism, transport, and receptor interactions.
  • Enzyme Substrate/Analyte: Employed in enzymatic assays and diagnostic test development related to hepatobiliary function.
  • Chemical Synthesis: Acts as a chiral starting material or intermediate for the production of more complex steroid derivatives with potential biological activity.
  • Metabolite Standard: Utilized in analytical laboratories (LC-MS, HPLC) for the identification and quantification of bile acid metabolites in biological samples.

Basic Information

Product Name (3A,5B,7B)-7-Hydroxy-3-(Sulfooxy)-Cholan-24-Oic Acid
CAS No. 68780-73-4
Molecular Formula C₂₄H₄₀O₈S
Molecular Weight 488.63 g/mol
Synonyms 7-Hydroxy-3-sulfooxycholan-24-oic Acid; 3-Sulfate of 7-Hydroxycholic Acid; Tauro-7-Hydroxycholic Acid Sulfate (isomeric form); 7α-Hydroxy-3β-sulfooxy-5β-cholan-24-oic Acid; 3-Sulfated 7-Hydroxy Cholic Acid; Cholan-24-oic acid, 7-hydroxy-3-(sulfooxy)-, (3α,5β,7β)-; Bile Acid Sulfate Derivative
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Quality Control

Our (3A,5B,7B)-7-Hydroxy-3-(Sulfooxy)-Cholan-24-Oic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Residue on Ignition ≤ 1.0%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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