Description

(5R,6S)-3-[[2-(Acetylamino)Ethenyl]Thio]-6-[(R)-1-Hydroxyethyl]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid is a key advanced pharmaceutical intermediate, specifically a penem derivative, critical for the synthesis of certain carbapenem antibiotics. Its precise stereochemistry and functional groups make it an essential building block for developing potent, broad-spectrum antibacterial agents. This compound is primarily required by pharmaceutical R&D laboratories and manufacturers engaged in the production of novel β-lactam antibiotics.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial intermediate in the multi-step synthesis of carbapenem-class antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and development of new β-lactam derivatives with improved efficacy and resistance profiles.
• Process Chemistry Optimization: Employed in scaling up and optimizing synthetic routes for antibiotic production in pilot plants and commercial manufacturing.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory submissions in antibiotic manufacturing.
• Antibacterial Agent Precursor: Functions as the core scaffold for constructing molecules that inhibit bacterial cell wall synthesis.

Basic Information

Product Name	(5R,6S)-3-[[2-(Acetylamino)Ethenyl]Thio]-6-[(R)-1-Hydroxyethyl]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid
CAS No.	68738-07-8
Molecular Formula	C13H16N2O5S
Molecular Weight	312.34 g/mol
Synonyms	(5R,6S)-3-[(2-Acetamidovinyl)thio]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; 6-[(1R)-1-Hydroxyethyl]-3-[(2-acetamidovinyl)thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; Penem derivative intermediate; Carbapenem intermediate; (5R,6S)-3-(2-Acetamidovinylthio)-6-[(R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our (5R,6S)-3-[[2-(Acetylamino)Ethenyl]Thio]-6-[(R)-1-Hydroxyethyl]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.