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1,3,4,6-Tetra-o-Acetyl-2-Azido-2-Deoxy-α-D-Mannopyranose CAS NO 68733-20-0
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CAS No.:68733-20-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1,3,4,6-Tetra-o-Acetyl-2-Azido-2-Deoxy-α-D-Mannopyranose is a key protected sugar derivative and a vital synthetic intermediate in carbohydrate chemistry. This compound is essential for the efficient synthesis of complex oligosaccharides and glycoconjugates, enabling precise control over stereochemistry and functional group manipulation. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for developing novel therapeutics, vaccines, and molecular probes.
Application
- Glycosylation Reagent: A crucial building block for the stereoselective synthesis of mannose-containing oligosaccharides and glycans.
- Pharmaceutical Intermediate: Used in the research and development of antiviral drugs, antibiotics, and other bioactive molecules that target carbohydrate-mediated processes.
- Glycoconjugate Synthesis: Serves as a precursor for creating glycoproteins, glycolipids, and neoglycoconjugates for immunological and diagnostic applications.
- Chemical Biology Probes: The azido group allows for further functionalization via click chemistry (e.g., CuAAC), enabling the creation of labeled sugars for metabolic labeling and imaging studies.
- Carbohydrate Library Development: A foundational material for combinatorial chemistry approaches to generate diverse sugar-based compound libraries for screening.
- Enzyme Substrate/Inhibitor Studies: Employed in biochemical research to study the mechanism and inhibition of glycosidases and glycosyltransferases.
Basic Information
| Product Name | 1,3,4,6-Tetra-o-Acetyl-2-Azido-2-Deoxy-α-D-Mannopyranose |
| CAS No. | 68733-20-0 |
| Molecular Formula | C14H19N3O9 |
| Molecular Weight | 373.32 g/mol |
| Synonyms | 2-Azido-2-deoxy-1,3,4,6-tetra-O-acetyl-α-D-mannopyranose; 2-Azido-1,3,4,6-tetra-O-acetyl-2-deoxy-α-D-mannopyranose; α-D-Mannopyranose, 2-azido-2-deoxy-, 1,3,4,6-tetraacetate; 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-mannose; Ac4ManNAz; Tetraacetylated Mannosamine Azide; 2-Azido-2-deoxy-mannose tetraacetate |
| EINECS | Contact for details |
Quality Control
Our 1,3,4,6-Tetra-o-Acetyl-2-Azido-2-Deoxy-α-D-Mannopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and correct stereochemical configuration. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and support your research and cGMP manufacturing requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Specific Rotation [α]D20 | Contact for details |
| Water Content (KF) | ≤ 0.5% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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