Description

Bicyclo[2.2.2]Octane-2-Carbonyl Chloride, 2-Methyl- (9Ci) is a highly functionalized, sterically hindered bicyclic acid chloride derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique, rigid three-dimensional structure is essential for constructing complex molecular architectures with precise stereochemistry and enhanced stability. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, specialty polymers, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific herbicides, fungicides, and plant growth regulators with improved efficacy.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Monomer: Employed in the polymerization reactions to produce specialty polymers with unique thermal and mechanical properties.
• Chemical Research & Development: A valuable tool for academic and industrial R&D in exploring new reaction pathways and constructing complex natural product analogs.
• Peptidomimetics & Bio-conjugation: Facilitates the introduction of the rigid bicyclo[2.2.2]octane scaffold into peptides and other biomolecules to modulate their conformation and stability.

Basic Information

Product Name	Bicyclo[2.2.2]Octane-2-Carbonyl Chloride, 2-Methyl- (9Ci)
CAS No.	68671-83-0
Molecular Formula	C10H15ClO
Molecular Weight	186.68 g/mol
Synonyms	2-Methylbicyclo[2.2.2]octane-2-carbonyl chloride; 2-Methyl-2-bicyclo[2.2.2]octanecarbonyl chloride; (2-Methylbicyclo[2.2.2]oct-2-yl)carbonyl chloride; 2-Methyl-2-bicyclo[2.2.2]octanecarboxylic acid chloride; 2-Methylbicyclo[2.2.2]octane-2-carboxylic acid chloride; 2-Methyl-2-bicyclo[2.2.2]octanoyl chloride
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octane-2-Carbonyl Chloride, 2-Methyl- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.