Description

1H-Indene-5-Carbonyl Chloride, 3-Cyano-2,3-Dihydro- (9Ci) is a specialized, high-value organic intermediate featuring a reactive acid chloride group and a cyano-substituted dihydroindene core. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic structures.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where the indene scaffold can contribute to unique biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: The reactive carbonyl chloride group allows for attachment to various scaffolds to create novel ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Fluorescent Probe Synthesis: The conjugated indene system can be utilized to build fluorescent markers and sensors for biochemical applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring precise functionalization of the indene ring system.

Basic Information

Item	Details
Product Name	1H-Indene-5-Carbonyl Chloride, 3-Cyano-2,3-Dihydro- (9Ci)
CAS No.	68634-09-3
Molecular Formula	C11H6ClNO
Molecular Weight	203.62 g/mol
Synonyms	3-Cyano-2,3-dihydro-1H-indene-5-carbonyl chloride; 2,3-Dihydro-3-cyano-1H-indene-5-carbonyl chloride; 5-(Chlorocarbonyl)-2,3-dihydro-1H-indene-3-carbonitrile; 3-Cyanoindan-5-carbonyl chloride; 68634-09-3; 1H-Indene-5-carbonyl chloride, 3-cyano-2,3-dihydro-
EINECS	Contact for details

Quality Control

Our 1H-Indene-5-Carbonyl Chloride, 3-Cyano-2,3-Dihydro- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening and protected from moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (e.g., DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.