Description

(3S)-Lonomycin A is a potent polyether ionophore antibiotic derived from *Streptomyces* species. This compound is valued for its high biological activity and specificity, making it a critical tool in biochemical research and development. It is primarily utilized by researchers in the pharmaceutical and life sciences industries for studying ion transport mechanisms and as a lead compound in antimicrobial discovery.

Application

• Biochemical Research: As a specific ionophore for studying transmembrane ion transport, particularly for monovalent cations.
• Antimicrobial Agent Development: Serves as a reference standard and a structural template for developing novel antibiotics.
• Veterinary Pharmaceutical Research: Investigated for potential applications in animal health due to its antiprotozoal and antibacterial properties.
• Cell Biology Studies: Used to manipulate intracellular ion concentrations to study cell signaling and apoptosis.
• Microbiology: Employed as a selective agent in microbial culture media and for studying bacterial resistance mechanisms.
• Pharmaceutical Reference Standard: Used for quality control, method development, and validation in analytical laboratories.

Basic Information

Product Name	(3S)-Lonomycin A
CAS No.	68567-60-2
Molecular Formula	C₃₄H₆₂O₁₁
Molecular Weight	646.86 g/mol
Synonyms	Lonomycin A; Lonomycin; (3S)-Lonomycin; Antibiotic 2230-C; Antibiotic 2230C; Lonomycin A sodium salt (derivative); Lonomycin A free acid; Streptomyces ribosidificus metabolite
EINECS	Contact for details

Quality Control

Our (3S)-Lonomycin A is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and potency. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.