Description

5,6-Dihydro-6-Hydroxythymidine is a modified nucleoside derivative of thymidine, featuring a reduced and hydroxylated pyrimidine ring. This specific molecular structure makes it a valuable intermediate and building block in advanced organic synthesis and pharmaceutical research. It is primarily utilized by researchers and manufacturers in the fields of nucleoside chemistry, antiviral drug development, and oligonucleotide synthesis. The compound's unique properties facilitate the creation of novel analogs for probing biological mechanisms and developing targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside analogs with potential antiviral or anticancer activity.
• Oligonucleotide Synthesis: Used in the research and development of modified DNA/RNA strands for diagnostic tools, antisense therapy, and basic biochemical research.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to understand DNA metabolism and repair pathways.
• Prodrug Development: Investigated for the design of prodrugs aimed at improving the bioavailability and targeting of nucleoside-based therapeutics.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5,6-Dihydro-6-Hydroxythymidine
CAS No.	68509-78-4
Molecular Formula	C10H16N2O6
Molecular Weight	260.24 g/mol
Synonyms	6-Hydroxy-5,6-dihydrothymidine; Dihydro-6-hydroxythymidine; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-5,6-dihydropyrimidine-2,4(1H,3H)-dione; 5,6-Dihydrothymidine-6-ol; Thymidine, 5,6-dihydro-6-hydroxy-
EINECS	Contact for details

Quality Control

Our 5,6-Dihydro-6-Hydroxythymidine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. We provide Certificates of Analysis (COA) with every shipment, detailing all test results to ensure traceability and compliance with your research or production standards. Our commitment is to deliver material of consistent, high quality for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.