Description

17-Dehydro-21-Hydroxy Hydrocortisone is a key synthetic steroid intermediate, specifically a derivative of hydrocortisone. This compound is valued for its role in the synthesis of more complex and potent corticosteroid pharmaceuticals. It is primarily required by research institutions and pharmaceutical manufacturers engaged in steroid chemistry and drug development.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of advanced corticosteroid APIs (Active Pharmaceutical Ingredients).
• Steroid Research & Development: Used in academic and industrial laboratories for studying structure-activity relationships (SAR) of steroid hormones.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Process Chemistry: Employed in the development and scale-up of manufacturing processes for anti-inflammatory and immunosuppressant drugs.

Basic Information

Product Name	17-Dehydro-21-Hydroxy Hydrocortisone
CAS No.	68473-77-8
Molecular Formula	C21H28O5
Molecular Weight	360.45 g/mol
Synonyms	21-Hydroxy-17-dehydrocortisone; 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione; 17-Dehydrocortisol; 17(20)-Dehydrohydrocortisone; Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, (11β)-; Hydrocortisone 17-dehydro derivative
EINECS	Contact for details

Quality Control

Our 17-Dehydro-21-Hydroxy Hydrocortisone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.