Description

5-Bromouridine 5'-Monophosphate Sodium Salt is a modified nucleotide monophosphate essential for biochemical research and pharmaceutical development. This compound serves as a critical building block for the synthesis of oligonucleotides and probes, enabling studies on RNA structure, function, and metabolism. It is primarily utilized by researchers and manufacturers in the fields of molecular biology, antiviral drug discovery, and diagnostic assay development.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor for incorporating brominated uridine into synthetic RNA strands for structural and functional studies.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays to study RNA polymerase, kinase, and phosphatase activity.
• Antiviral Drug Development: Investigated as a potential metabolite or prodrug in the research of nucleoside analogue-based antiviral therapies.
• RNA Labeling & Detection: Facilitates the creation of labeled RNA probes for hybridization, Northern blotting, and other detection methodologies.
• Structural Biology: Employed in X-ray crystallography and NMR spectroscopy to solve RNA structures and investigate ligand interactions.
• Diagnostic Reagents: Used in the development of diagnostic kits and assays that require specific nucleotide sequences or modifications.

Basic Information

Product Name	5-Bromouridine 5'-Monophosphate Sodium Salt
CAS No.	68244-51-9
Molecular Formula	C9H11BrN2O9P • xNa
Molecular Weight	Contact for details
Synonyms	5-Bromo-UMP sodium salt; 5-BrUMP Na; BrUMP sodium salt; 5-Bromouridylic acid sodium salt; 5-Bromo-2'-deoxyuridine 5'-monophosphate sodium salt (common misnomer); 5-Br-uridine-5'-monophosphate sodium; Uridine, 5-bromo-, 5'-(dihydrogen phosphate), sodium salt
EINECS	Contact for details

Quality Control

Our 5-Bromouridine 5'-Monophosphate Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with lot-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.