Description

24,25-Epoxycholesterol is a specific oxysterol derivative of cholesterol, playing a significant role in the study of cholesterol biosynthesis and metabolism. This compound is a valuable biochemical research tool and a key intermediate for investigating regulatory pathways in lipid biology. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotech companies focused on metabolic diseases, atherosclerosis, and novel therapeutic discovery.

Application

• Biochemical Research: Used as a reference standard and intermediate in studies of cholesterol biosynthesis, particularly the 24,25-epoxycholesterol pathway.
• Pharmaceutical Development: Serves as a key starting material or intermediate in the synthesis of potential drug candidates targeting liver X receptors (LXRs) and cholesterol homeostasis.
• Metabolic Disease Studies: Employed in research models to investigate atherosclerosis, lipid disorders, and related metabolic syndromes.
• Cell Signaling Research: Utilized to study the role of oxysterols as signaling molecules in cellular processes and immune function.
• Analytical Standard: Acts as a high-purity standard for HPLC, LC-MS, and GC-MS analysis in analytical laboratories for quality control and method validation.
• Enzyme Inhibition Studies: Applied in assays to investigate the activity and inhibition of enzymes like sterol epoxide hydrolase.

Basic Information

Product Name	24,25-Epoxycholesterol
CAS No.	68138-65-8
Molecular Formula	C27H44O2
Molecular Weight	400.64 g/mol
Synonyms	(24S)-24,25-Epoxycholesterol; 24,25-Epoxycholest-5-en-3β-ol; 5-Cholesten-3β-ol, 24,25-epoxy-, (24S)-; 24(S),25-Epoxycholesterol; 24,25-EC; 24,25-Epoxy-cholesterol; 24,25-Epoxycholest-5-en-3β-ol (24S); 24,25-Epoxycholest-5-en-3-ol, (3β,24S)-
EINECS	Contact for details

Quality Control

Our 24,25-Epoxycholesterol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.