Description

5-β-Pregnan-3-Alpha, 6-Alpha, 21-Triol-20-One is a high-purity steroid derivative of significant interest in pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of specialized steroid hormones and related APIs.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of steroid products via HPLC, GC-MS, or other chromatographic techniques.
• Biochemical Research: Employed in metabolic pathway studies, enzyme inhibition assays, and receptor binding studies to understand steroid biochemistry and physiology.
• Process Development: Serves as a starting material or intermediate for scaling up production processes under cGMP conditions for clinical trial material.

Basic Information

Item	Detail
Product Name	5-β-Pregnan-3-Alpha, 6-Alpha, 21-Triol-20-One
CAS No.	67896-70-2
Molecular Formula	C21H34O4
Molecular Weight	350.50 g/mol
Synonyms	5β-Pregnane-3α,6α,21-triol-20-one; 3α,6α,21-Trihydroxy-5β-pregnan-20-one; 20-Oxo-5β-pregnane-3α,6α,21-triol; 5β-Pregnan-3α,6α,21-triol-20-one; Pregnane-3α,6α,21-triol-20-one, 5β-
EINECS	Contact for details

Quality Control

Our 5-β-Pregnan-3-Alpha, 6-Alpha, 21-Triol-20-One is manufactured and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) upon request, which include data from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment supports applications requiring research-grade to cGMP-compliant materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.