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1,3,4,6-Tetra-o-Acetyl-2-Azido-2-Deoxy-α-D-Galactopyranose CAS NO 67817-30-5


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CAS No.:67817-30-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,3,4,6-Tetra-o-Acetyl-2-Azido-2-Deoxy-α-D-Galactopyranose is a key protected monosaccharide derivative, widely utilized as a versatile building block in synthetic carbohydrate chemistry. Its value lies in its reactive azido and acetyl protecting groups, which enable precise and efficient glycosylation reactions for constructing complex oligosaccharides. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of glycoconjugate vaccines, diagnostic reagents, and novel therapeutic agents.

Application

  • Glycoconjugate Vaccine Synthesis: A critical precursor for constructing antigenic carbohydrate chains used in modern bacterial and cancer vaccines.
  • Oligosaccharide & Glycopeptide Assembly: Serves as a fundamental glycosyl donor or acceptor in automated and solution-phase synthesis of complex bioactive carbohydrates.
  • Pharmaceutical Intermediate: Used in the research and production of glycosidase inhibitors, antiviral drugs, and other carbohydrate-based therapeutics.
  • Diagnostic Reagent Development: Employed to create labeled glycans and probes for studying carbohydrate-protein interactions and diagnostic assays.
  • Chemical Biology Research: A valuable tool for probing glycosylation pathways and developing glycomimetics due to its bio-orthogonal azido functionality.
  • Standards & Reference Materials: Supplied as a high-purity standard for analytical method development and quality control in glycan analysis.

Basic Information

Product Name 1,3,4,6-Tetra-o-Acetyl-2-Azido-2-Deoxy-α-D-Galactopyranose
CAS No. 67817-30-5
Molecular Formula C14H19N3O9
Molecular Weight 373.32 g/mol
Synonyms 2-Azido-2-deoxy-1,3,4,6-tetra-O-acetyl-α-D-galactopyranose; 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-galactopyranose; α-D-Galactopyranose, 2-azido-2-deoxy-, 1,3,4,6-tetraacetate; 2-Azido-1,3,4,6-tetra-O-acetyl-2-deoxy-α-D-galactose; Ac4GalNAz α; Tetraacetylated GalNAz α-anomer; GalNAz(Ac)4-α
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Quality Control

Our 1,3,4,6-Tetra-o-Acetyl-2-Azido-2-Deoxy-α-D-Galactopyranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP starting material standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Specific Rotation [α]20/D +120° to +130° (c=1 in CHCl3)
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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