Description

5'-Thioadenosine is a sulfur-modified nucleoside analog where the oxygen atom in the ribose ring is replaced by a sulfur atom at the 5' position. This structural modification confers unique biochemical properties, making it a valuable tool compound and intermediate in life science research and pharmaceutical development. It is primarily utilized by researchers in biochemistry, enzymology, and medicinal chemistry. The product is supplied under the identifier CAS NO 67805-97-4.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for methyltransferases and other sulfur-metabolizing enzymes.
• Medicinal Chemistry: Serves as a key synthetic intermediate for the development of novel antiviral and anticancer nucleoside analogs.
• Metabolic Pathway Analysis: Employed as a probe to study sulfur incorporation pathways and nucleotide salvage mechanisms in cellular systems.
• Enzyme Mechanism Studies: Acts as a mechanistic probe to investigate the role of specific functional groups in enzyme-substrate interactions.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for pharmaceutical development.

Basic Information

Product Name	5'-Thioadenosine
CAS No.	67805-97-4
Molecular Formula	C10H13N5O3S
Molecular Weight	283.31 g/mol
Synonyms	Adenosine, 5'-thio-; 5'-Thioadenosine; 5'-S-Deoxy-5'-thioadenosine; 9-β-D-5'-Thioribofuranosyladenine; 5'-Thio-5'-deoxyadenosine; NSC 154890; 5'-S-(Adenosin-5'-yl) thioadenosine
EINECS	Contact for details

Quality Control

Our 5'-Thioadenosine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as confirmed by HPLC, NMR, and mass spectrometry. The product is suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.