Description

Guanosine, 8-(Acetyl(4'-Fluoro(1,1'-Biphenyl)-4-Yl)Amino)-2'-Deoxy- is a chemically modified nucleoside analog, a key building block in advanced pharmaceutical research and development. This compound matters for its role as a sophisticated intermediate in the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing next-generation nucleotide-based therapies.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used in studies investigating enzyme mechanisms, particularly those involving DNA polymerases and kinases.
• Probe Development: Serves as a modified base for creating fluorescent or affinity-labeled probes for nucleic acid detection and sequencing.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
• Academic Research: Utilized in university and institutional labs for fundamental research in chemical biology and nucleoside chemistry.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Product Name	Guanosine, 8-(Acetyl(4'-Fluoro(1,1'-Biphenyl)-4-Yl)Amino)-2'-Deoxy-
CAS No.	67764-18-5
Molecular Formula	C25H25FN6O5
Molecular Weight	508.50 g/mol
Synonyms	8-[N-Acetyl-N-[4'-(4-fluorobiphenyl)]]amino-2'-deoxyguanosine; 2'-Deoxy-8-[[[4'-(4-fluorobiphenyl)]acetyl]amino]guanosine; 8-((4'-Fluoro-[1,1'-biphenyl]-4-yl)acetamido)-2'-deoxyguanosine; Modified 2'-Deoxyguanosine Derivative; Fluorinated Biphenyl Guanosine Analog; Nucleoside Research Chemical; CAS 67764-18-5
EINECS	Contact for details

Quality Control

Our Guanosine, 8-(Acetyl(4'-Fluoro(1,1'-Biphenyl)-4-Yl)Amino)-2'-Deoxy- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.