Description

(5β,6α)-6-Hydroxy-3-Oxo-Cholan-24-Oic Acid is a high-purity bile acid derivative, a key intermediate in the synthesis of pharmaceutical compounds. This compound is valued for its specific stereochemistry and functional groups, which are critical for research and development in medicinal chemistry. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for the production of advanced therapeutic agents and biochemical research.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of steroid-based drugs and therapeutic agents targeting liver and metabolic functions.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies and metabolic pathway research related to bile acid metabolism.
• Fine Chemical Synthesis: Serves as a chiral starting material or intermediate for the production of complex, high-value specialty chemicals.
• Reference Material: Employed in analytical laboratories for method development, calibration, and quality control of related pharmaceutical products.
• Metabolite Studies: Utilized in the study of drug metabolism and pharmacokinetics (DMPK) for compounds with similar steroidal backbones.

Basic Information

Product Name	(5β,6α)-6-Hydroxy-3-Oxo-Cholan-24-Oic Acid
CAS No.	67733-54-4
Molecular Formula	C24H38O5
Molecular Weight	406.56 g/mol
Synonyms	6α-Hydroxy-3-oxocholan-24-oic Acid; 6α-Hydroxy-3-oxo-5β-cholan-24-oic Acid; 3-Oxo-6α-hydroxy-5β-cholan-24-oic Acid; 6-Hydroxy-3-oxocholanic Acid; 6α-Hydroxy-3-oxolithocholic Acid; 3-Oxo-6α-hydroxylithocholic Acid; Hyodeoxycholic Acid 3-Oxide Derivative
EINECS	Contact for details

Quality Control

Our (5β,6α)-6-Hydroxy-3-Oxo-Cholan-24-Oic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide a Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.