Description

Bicyclo[2.2.1]Heptane-2-Carbonyl Chloride, 3,3-Dimethyl-, (1R-Exo)- (9Ci) is a high-purity, stereochemically defined acid chloride derivative of a dimethyl-substituted norbornane framework. This compound is a critical chiral building block for the synthesis of complex organic molecules, offering a rigid, three-dimensional structure that is highly valuable in advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its bicyclic structure can impart unique biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer and Material Science: Acts as a monomer or cross-linking agent for creating polymers with specific thermal and mechanical properties, such as epoxy resins or advanced composites.
• Flavor and Fragrance Chemistry: Employed in the synthesis of complex, high-value aroma chemicals that require a specific stereochemistry and robust molecular backbone.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic synthesis and for exploring new chemical spaces in discovery chemistry.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Carbonyl Chloride, 3,3-Dimethyl-, (1R-Exo)- (9Ci)
CAS No.	67596-91-2
Molecular Formula	C10H15ClO
Molecular Weight	186.68 g/mol
Synonyms	(1R-exo)-3,3-Dimethylbicyclo[2.2.1]heptane-2-carbonyl chloride; exo-3,3-Dimethyl-2-norbornanecarbonyl chloride; (1R,2S,4R)-3,3-Dimethylbicyclo[2.2.1]heptane-2-carbonyl chloride; 3,3-Dimethyl-2-norbornanecarboxylic acid chloride; (1R)-exo-3,3-Dimethylbicyclo[2.2.1]heptane-2-carbonyl chloride; endo,exo-3,3-Dimethylbicyclo[2.2.1]heptane-2-carbonyl chloride (isomeric mixture reference); 2-Norbornanecarbonyl chloride, 3,3-dimethyl-, (1R-exo)-
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[2.2.1]Heptane-2-Carbonyl Chloride, 3,3-Dimethyl-, (1R-Exo)- (9Ci) is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and enantiomeric excess meet the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) detailing specifications such as assay (by GC/HPLC), chiral purity, and impurity profiles are available for every shipment. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and acid chloride nature, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from strong bases, oxidizers, and moisture. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.