Description

1H-Pyrazole-1-Carbonyl Chloride, 4-Chloro-3-Methyl- (9Ci) is a highly reactive acid chloride derivative of a substituted pyrazole, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the pyrazole-carbonyl moiety into target molecules, facilitating the development of novel compounds with specific functionalities. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and fine chemicals where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of novel therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the pyrazole core imparts specific biological activity.
• Material Science Research: Employed in the creation of specialized polymers, ligands, or metal-organic frameworks (MOFs) with tailored properties.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation, labeling biomolecules, or developing activity-based probes.
• Fine Chemical Production: Serves as a precursor for synthesizing complex dyes, pigments, and other high-value specialty chemicals.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	1H-Pyrazole-1-Carbonyl Chloride, 4-Chloro-3-Methyl- (9Ci)
CAS No.	67514-72-1
Molecular Formula	C5H4Cl2N2O
Molecular Weight	178.99 g/mol
Synonyms	4-Chloro-3-methyl-1H-pyrazole-1-carbonyl chloride; 4-Chloro-3-methylpyrazole-1-carbonyl chloride; 3-Methyl-4-chloro-1H-pyrazole-1-carbonyl chloride; 1-Carbonylchloride-4-chloro-3-methylpyrazole; 4-Chloro-3-methyl-1-pyrazolecarbonyl chloride; (4-Chloro-3-methyl-1H-pyrazol-1-yl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazole-1-Carbonyl Chloride, 4-Chloro-3-Methyl- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including chromatography and spectroscopy, to verify identity and quantify impurities. Certificates of Analysis (COA) detailing all relevant specifications are provided to guarantee the material meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Due to its reactivity as a strong acid/organic solvent derivative, it should be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from moisture, bases, and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.