Description

1H-Pyrazole-1-Carbonyl Chloride, 3,4,5-Trimethyl- (9Ci) is a specialized heterocyclic acid chloride building block, CAS NO 67514-64-1. It serves as a critical reagent for introducing the 3,4,5-trimethylpyrazole-1-carbonyl moiety, enabling the synthesis of novel compounds with tailored properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the pyrazole core imparts specific biological activity.
• Organic Synthesis Reagent: Acts as an acylating agent for amines and alcohols to create amides and esters in complex multi-step synthetic routes.
• Material Science Research: Employed in the development of specialty polymers, ligands for catalysis, and other functional materials.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in proteomics and biochemical research due to its reactive carbonyl chloride group.

Basic Information

Product Name	1H-Pyrazole-1-Carbonyl Chloride, 3,4,5-Trimethyl- (9Ci)
CAS No.	67514-64-1
Molecular Formula	C7H9ClN2O
Molecular Weight	172.61 g/mol
Synonyms	3,4,5-Trimethyl-1H-pyrazole-1-carbonyl chloride; 3,4,5-Trimethylpyrazole-1-carbonyl chloride; 1-Carbonylchloride-3,4,5-trimethylpyrazole; 3,4,5-Trimethyl-1-pyrazolecarbonyl chloride; Trimethylpyrazole carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-1-Carbonyl Chloride, 3,4,5-Trimethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) documenting all critical parameters are provided to guarantee consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.