Description

Calamine is a time-honored, soothing topical preparation primarily composed of zinc oxide and a small amount of ferric oxide, widely recognized for its skin-protective and astringent properties. Its core value lies in providing effective, gentle relief from minor skin irritations, itching, and discomfort, making it a staple in dermatological and first-aid formulations. This product is essential for manufacturers in the pharmaceutical, over-the-counter (OTC) drug, and personal care industries producing medicated lotions, creams, and calamine-based preparations.

Application

• Topical Pharmaceutical Preparations: As the active ingredient in soothing lotions, creams, and ointments for the relief of itching, pain, and discomfort from poison ivy, oak, sumac, insect bites, and minor skin rashes.
• Dermatological Care Products: Used in formulations for acne treatments, diaper rash creams, and products designed for sensitive or irritated skin due to its mild astringent and protective qualities.
• First-Aid and After-Sun Products: A key component in first-aid sprays, gels, and after-sun care lotions to cool, soothe, and protect damaged or sunburned skin.
• Cosmetic and Personal Care: Incorporated into certain makeup foundations, facial masks, and medicated powders where skin-soothing and oil-absorbing properties are desired.
• Veterinary Applications: Used in topical preparations for animals to address skin irritations, hot spots, and minor wounds.

Basic Information

Product Name	Calamine
CAS No.	67479-94-1
Molecular Formula	ZnO·xFe₂O₃ (Composite)
Molecular Weight	N/A (Composite Material)
Synonyms	Prepared Calamine; Calaminum Praeparatum; Zinc Oxide with Ferric Oxide; Calamine Lotion USP; Pink Calamine; Calamine (Topical); Zinc Carbonate Hydroxide, Ferric Oxide Mixture; Zinc Oxide-Calcium Hydroxide-Ferric Oxide Mixture
EINECS	Contact for details

Quality Control

Our Calamine is manufactured and tested to meet stringent pharmacopeial standards, ensuring consistency and efficacy for critical topical applications. We adhere to relevant monographs such as USP-NF (United States Pharmacopeia) and BP (British Pharmacopoeia) for identity, assay, and impurity profiles. Every batch is supported by a comprehensive Certificate of Analysis (COA), verifying compliance with specified limits for zinc oxide content, iron content, and absence of heavy metals. Certificates are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store in a cool, dry place at controlled room temperature (15-25°C). Ensure the storage area has low humidity to prevent caking and maintain product integrity. Keep away from incompatible materials.

Specification

Item	Specification
Description	A pink powder
Identification (IR)	Conforms
Assay (ZnO)	98.0 - 100.5%
Iron Content (as Fe)	0.5 - 1.5%
Loss on Drying	≤ 1.0%
Acid-Insoluble Substances	≤ 1.0%
Heavy Metals	≤ 20 ppm
Microbial Limits	Meets USP <61> and <62>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.