Description

2-Amino-8-D-Ribofuranosyl-Imidazo[1,2-A]-1,3,5-Triazin-4(8H)-One is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel antiviral and anticancer agents, particularly those targeting viral polymerases and cellular replication pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside-based antiviral drugs and experimental oncology treatments.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving polymerases and nucleoside metabolic pathways.
• Antiviral Agent Development: Serves as a core scaffold for creating novel compounds active against DNA and RNA viruses.
• Oncology Research: Investigated for its potential incorporation into prodrugs or targeted cancer therapies that interfere with nucleotide synthesis.
• Molecular Biology: Can be used in the study of nucleic acid chemistry and the development of modified oligonucleotides.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a complex, functionalized ribofuranosyl building block.

Basic Information

Product Name	2-Amino-8-D-Ribofuranosyl-Imidazo[1,2-A]-1,3,5-Triazin-4(8H)-One
CAS No.	67410-65-5
Molecular Formula	C11H14N6O5
Molecular Weight	310.27 g/mol
Synonyms	8-β-D-Ribofuranosylimidazo[1,2-a]-1,3,5-triazin-4(8H)-one, 2-Amino-; 2-Aminoimidazo[1,2-a]-1,3,5-triazin-4(8H)-one, 8-β-D-ribofuranosyl-; 2-Amino-8-β-D-ribofuranosylimidazo[1,2-a]-1,3,5-triazin-4(8H)-one; Imidazo[1,2-a]-1,3,5-triazin-4(8H)-one, 2-amino-8-β-D-ribofuranosyl-; NSC 401005; 2-Amino-8-β-D-ribofuranosylimidazo[1,2-a]-1,3,5-triazin-4(8H)-one
EINECS	Contact for details

Quality Control

Our 2-Amino-8-D-Ribofuranosyl-Imidazo[1,2-A]-1,3,5-Triazin-4(8H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.