Description

(24R)-27-Nor-5β-Cholestane-3α,7α,12α,24,26-Pentaol CAS NO 67392-10-3 is a high-purity, polyhydroxylated sterol derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical intermediate and reference standard for studying bile acid biosynthesis and metabolic pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on metabolic disease research, steroid chemistry, and the synthesis of novel therapeutic agents.

Application

• Biochemical Research Intermediate: A key precursor in the study of bile acid synthesis and cholesterol metabolism pathways.
• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in the production of sterol-based APIs.
• Metabolic Pathway Analysis: Employed in enzymatic studies to investigate the function of hydroxylases and other metabolic enzymes.
• Fine Chemical Synthesis: Serves as a sophisticated building block for the synthesis of complex steroidal compounds with potential biological activity.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry and biochemistry.

Basic Information

Item	Detail
Product Name	(24R)-27-Nor-5β-Cholestane-3α,7α,12α,24,26-Pentaol
CAS No.	67392-10-3
Molecular Formula	C26H44O5
Molecular Weight	436.63 g/mol
Synonyms	27-Norcholestane-3α,7α,12α,24,26-pentaol; (24R)-27-Nor-5β-cholestane-3α,7α,12α,24,26-pentol; 3α,7α,12α,24,26-Pentahydroxy-27-nor-5β-cholestane; 27-Nor-5β-cholestane-3α,7α,12α,24,26-pentaol; 5β-Cholestane-3α,7α,12α,24,26-pentaol, 27-nor-; A key intermediate in 25-hydroxylation side chain cleavage of 5β-cholestane-3α,7α,12α-triol
EINECS	Contact for details

Quality Control

Every batch of (24R)-27-Nor-5β-Cholestane-3α,7α,12α,24,26-Pentaol is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.