Description

5'-Deoxy-5'-(Isobutylthio)-3-Deazaadenosine is a chemically modified nucleoside analog of significant interest in biochemical and pharmaceutical research. This compound serves as a valuable tool for investigating and modulating purinergic signaling pathways and related enzymatic processes. It is primarily utilized by research scientists and development teams in the fields of medicinal chemistry, enzymology, and molecular biology for the development of novel therapeutic agents and diagnostic tools.

Application

• Biochemical Research: Used as a potent inhibitor or substrate analog in studies of S-adenosylhomocysteine hydrolase and other methyltransferase enzymes.
• Medicinal Chemistry: Serves as a key intermediate or lead compound in the synthesis and development of antiviral and anticancer agents.
• Enzyme Mechanism Studies: Employed to probe the structure-activity relationships and catalytic mechanisms of nucleoside-processing enzymes.
• Pharmaceutical Development: Investigated for its potential role in modulating cellular signaling pathways relevant to inflammation and immune response.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5'-Deoxy-5'-(Isobutylthio)-3-Deazaadenosine
CAS No.	67377-76-8
Molecular Formula	C15H23N5O3S
Molecular Weight	353.44 g/mol
Synonyms	3-Deaza-5'-deoxy-5'-(isobutylthio)adenosine; 5'-Deoxy-5'-(2-methylpropylthio)-3-deazaadenosine; 3-Deaza-SIBA; 3-Deaza-5'-isobutylthioadenosine; 5'-(Isobutylthio)-3-deazaadenosine; 3-Deaza-5'-deoxy-5'-(isobutylthio)adenosine; SIBA analog; AdoHcy hydrolase inhibitor analog
EINECS	Contact for details

Quality Control

Our 5'-Deoxy-5'-(Isobutylthio)-3-Deazaadenosine is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for research applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request, supporting compliance with rigorous laboratory standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.