Description

2-Chloro-1-Methyl-1H-Indole-3-Carbonyl Chloride is a high-purity, reactive indole derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functional groups, enabling precise and efficient construction of complex heterocyclic frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used to construct indole-based scaffolds for developing new-generation herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functionalizing agent for creating specialized polymers and organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate for producing high-value, complex indole-derived colorants and fluorescent markers.
• Academic & R&D: A versatile reagent for methodological studies in organic chemistry and heterocyclic compound library development.
• Custom Synthesis: Building block for contract research organizations (CROs) and CDMOs producing bespoke molecules for client projects.

Basic Information

Product Name	2-Chloro-1-Methyl-1H-Indole-3-Carbonyl Chloride
CAS No.	67342-12-5
Molecular Formula	C11H7Cl2NO
Molecular Weight	240.09 g/mol
Synonyms	2-Chloro-1-methylindole-3-carbonyl chloride; 1-Methyl-2-chloroindole-3-carbonyl chloride; 2-Chloro-1-methyl-1H-indole-3-carboxylic acid chloride; 3-Carbonyl chloride-2-chloro-1-methylindole; 67342-12-5; 2-Chloro-1-methylindole-3-carboxylic acid chloride; 1H-Indole-3-carbonyl chloride, 2-chloro-1-methyl-
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-1-Methyl-1H-Indole-3-Carbonyl Chloride is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.