Description

Guanosine-2-Deoxy-2-Fluoro-D-Glucose Diphosphate Ester is a specialized nucleotide sugar derivative, a key intermediate in the synthesis of modified nucleosides and nucleotides. This compound is critical for research and development in the pharmaceutical and biotechnology sectors, particularly in the study of metabolic pathways and the development of novel antiviral and anticancer agents. It is primarily utilized by research institutions, diagnostic developers, and pharmaceutical companies engaged in advanced biochemical synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases and metabolic enzymes.
• Diagnostic Probe Development: Serves as a precursor for labeled compounds used in molecular imaging and diagnostic assays.
• Metabolic Pathway Analysis: Employed in research to trace and understand glucose metabolism and nucleotide sugar utilization in cells.
• Glycobiology Studies: Used in the synthesis of complex carbohydrates and glycoconjugates for structural and functional studies.
• Enzyme Mechanism Studies: Acts as a tool compound to investigate the specificity and catalytic mechanisms of glycosyltransferases and related enzymes.

Basic Information

Product Name	Guanosine-2-Deoxy-2-Fluoro-D-Glucose Diphosphate Ester
CAS No.	67341-45-1
Molecular Formula	C₁₆H₂₃FN₅O₁₃P₂
Molecular Weight	589.33 g/mol
Synonyms	2'-Deoxy-2'-fluoroguanosine 5'-(trihydrogen diphosphate), P1-(2-Deoxy-2-fluoro-α-D-glucopyranosyl) P2-guanosine-5'-diphosphate, GDP-2FGlc, Guanosine 5'-(2-deoxy-2-fluoro-α-D-glucopyranosyl diphosphate), 2-Fluoro-2-deoxyglucose-guanosine diphosphate, Guanosine diphosphate 2-fluoro-2-deoxy-D-glucose
EINECS	Contact for details

Quality Control

Our Guanosine-2-Deoxy-2-Fluoro-D-Glucose Diphosphate Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.