Description

2-(6-Amino-9H-Purin-9-Yl)-4-(Benzylamino)-5-(Hydroxymethyl)Tetrahydrofuran-3-Ol is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel antiviral and anticancer agents, where its specific structural modifications are key to modulating biological activity. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleotide-based therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral drugs targeting viral polymerases.
• Anticancer Agent Research: Used in the development and screening of potential chemotherapeutic compounds that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to understand nucleotide metabolism and related pathways.
• Prodrug Development: Serves as a core structure for designing prodrugs with improved bioavailability and targeted delivery.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study cellular processes involving purine recognition.

Basic Information

Product Name	2-(6-Amino-9H-Purin-9-Yl)-4-(Benzylamino)-5-(Hydroxymethyl)Tetrahydrofuran-3-Ol
CAS No.	67313-10-4
Molecular Formula	C₁₇H₂₀N₆O₃
Molecular Weight	356.38 g/mol
Synonyms	9-[(2S,3S,4R,5R)-3-(Benzylamino)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-9H-purin-6-amine; 6-Amino-9-[3-(benzylamino)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]purine; N6-Benzylaminopurine Nucleoside Analog; Benzylamino Adenosine Derivative; 2-(6-Aminopurin-9-yl)-4-(benzylamino)-5-(hydroxymethyl)oxolane-3-ol; 67313-10-4; BzAdo Analog
EINECS	Contact for details

Quality Control

Our 2-(6-Amino-9H-Purin-9-Yl)-4-(Benzylamino)-5-(Hydroxymethyl)Tetrahydrofuran-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.