Description

4-Fluoro-3-Nitrophenyl Azide is a specialized aromatic azide compound, a key intermediate in advanced organic synthesis. Its value lies in its dual functionality, where the azide group serves as a versatile click chemistry handle and the electron-deficient aromatic ring directs further substitution. This compound is essential for researchers and manufacturers in the pharmaceutical and material science industries developing novel bioactive molecules, polymers, and photoaffinity labeling probes.

Application

• Click Chemistry Intermediate: A critical building block for Huisgen 1,3-dipolar cycloaddition reactions to create triazole linkages in drug discovery and polymer science.
• Photoaffinity Labeling (PAL): Used to study protein-ligand interactions and identify biological targets; the azide group generates a reactive nitrene upon UV irradiation for covalent bonding.
• Polymer Functionalization: Enables the introduction of fluorinated aromatic groups into polymer backbones or side chains to modify thermal stability, solubility, and electronic properties.
• Pharmaceutical Research: Serves as a precursor for synthesizing fluorinated nitroaromatic compounds with potential biological activity.
• Material Science: Used in the development of advanced materials, including surface modifiers, cross-linking agents, and components for electronic devices.
• Bioconjugation: Facilitates the attachment of fluorophores, tags, or other molecules to biomolecules for diagnostic and research applications.

Basic Information

Product Name	4-Fluoro-3-Nitrophenyl Azide
CAS No.	67312-96-3
Molecular Formula	C6H3FN4O2
Molecular Weight	182.11 g/mol
Synonyms	1-Azido-4-fluoro-3-nitrobenzene; 4-Fluoro-3-nitro-1-azidobenzene; 4-Fluoro-3-nitrophenyl azide; 3-Nitro-4-fluorophenyl azide; 1-Fluoro-2-nitro-4-azidobenzene; (4-Fluoro-3-nitrophenyl)azide; Azidobenzene, 4-fluoro-3-nitro-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Nitrophenyl Azide is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to the light-sensitive and potentially shock-sensitive nature of organic azides, handle and store with appropriate precautions, away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Standard Grade)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.