Description

Fenoldopam Mesylate is a selective dopamine D1 receptor agonist, widely recognized for its potent vasodilatory effects. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of finished pharmaceutical formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of medications for acute hypertension and severe blood pressure management.

Application

• Pharmaceutical API: Core active ingredient in injectable formulations for the treatment of hypertensive emergencies.
• Cardiovascular Research: A key reference standard and tool compound in preclinical studies investigating renal and systemic hemodynamics.
• Drug Development: Used in the synthesis and process development of novel dopamine receptor-targeting therapeutics.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories.
• Hospital Pharmacy Compounding: Employed in specialized compounding for critical care medication preparations, where applicable.

Basic Information

Product Name	Fenoldopam Mesylate
CAS No.	67227-57-0
Molecular Formula	C16H16ClNO3 • CH4O3S
Molecular Weight	401.87 g/mol
Synonyms	Fenoldopam Methanesulfonate; SKF-82526-J; 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol methanesulfonate; Corlopam (brand name); DA-1 receptor agonist; (6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-3-benzazepine-7,8-diol) monomethanesulfonate
EINECS	Contact for details

Quality Control

Our Fenoldopam Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and related substances, residual solvent analysis, and identification tests, to ensure compliance with in-house specifications aligned with ICH guidelines. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.