Description

n-[(3A,5B,7A)-7-Hydroxy-24-Oxo-3-(Sulfooxy)Cholan-24-Yl]-Glycine is a chemically modified bile acid derivative, a key intermediate in the synthesis of advanced pharmaceutical agents. Its value lies in its specific functional groups, which make it a crucial building block for creating targeted therapeutic compounds with enhanced bioavailability and metabolic profiles. This high-purity intermediate is essential for research and development laboratories and production facilities in the pharmaceutical and biotechnology sectors, particularly those focused on hepatobiliary and metabolic diseases.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel therapeutic agents targeting liver and metabolic pathways.
• Biochemical Research: Used as a reference standard or substrate in enzymatic and metabolic studies related to bile acid conjugation and transport.
• Prodrug Development: Serves as a key component in the design of prodrugs to improve drug solubility and targeted delivery.
• Metabolic Pathway Analysis: Employed in in-vitro and in-vivo studies to investigate the role of sulfated and glycine-conjugated bile acids.
• High-Value Fine Chemical Synthesis: Utilized in multi-step organic synthesis for creating complex, high-purity molecules for clinical trials.

Basic Information

Product Name	n-[(3A,5B,7A)-7-Hydroxy-24-Oxo-3-(Sulfooxy)Cholan-24-Yl]-Glycine
CAS No.	67030-54-0
Molecular Formula	C₂₆H₄₁NO₉S
Molecular Weight	543.67 g/mol
Synonyms	Glyco-7α-hydroxy-3-sulfooxy-24-nor-5β-cholan-24-oic acid; 3α-Sulfooxy-7α-hydroxy-5β-cholan-24-oyl glycine; Tauro-7α-hydroxy-3-sulfate-5β-cholan-24-oate analog; 7α-Hydroxy-3-sulfoxy-5β-cholan-24-oic acid N-(carboxymethyl)amide; N-(3α-Sulfooxy-7α-hydroxy-24-oxo-5β-cholan-24-yl)glycine; Glycine conjugate of 7α-hydroxy-3-sulfolithocholic acid; Bile acid sulfate glycine conjugate; 67030-54-0
EINECS	Contact for details

Quality Control

Our n-[(3A,5B,7A)-7-Hydroxy-24-Oxo-3-(Sulfooxy)Cholan-24-Yl]-Glycine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.