Description

4-(1-Pyrenyl)Butyl Methylphosphonofluoridate is a specialized organophosphorus compound characterized by a pyrene fluorophore linked to a phosphonofluoridate moiety. This unique structure makes it a valuable intermediate for the synthesis of advanced materials and biochemical probes, particularly in the development of fluorescent sensors and enzyme inhibitors. It is primarily utilized by research institutions and chemical manufacturers in the fields of analytical chemistry, materials science, and pharmaceutical research for creating novel diagnostic tools and functional polymers.

Application

• Fluorescent Probe Synthesis: Key intermediate for developing sensitive fluorescent sensors and labels for biological imaging and detection.
• Enzyme Inhibition Studies: Used in biochemical research to create potent, fluorescently-tagged inhibitors for studying enzyme kinetics and mechanisms.
• Advanced Material Development: Serves as a building block for creating novel polymers and organic electronic materials with specific photophysical properties.
• Chemical Biology Research: Employed in the design and synthesis of activity-based probes (ABPs) for profiling enzyme activities in complex biological systems.
• Pharmaceutical Intermediate: Potential precursor in the research and development of targeted therapeutic agents.
• Surface Modification Agent: Can be used to functionalize surfaces with pyrene groups for sensor or adhesion applications.

Basic Information

Product Name	4-(1-Pyrenyl)Butyl Methylphosphonofluoridate
CAS No.	67000-88-8
Molecular Formula	C25H24FO3P
Molecular Weight	422.43 g/mol
Synonyms	Methylphosphonofluoridic Acid 4-(1-Pyrenyl)Butyl Ester; 1-Pyrenebutanol Methylphosphonofluoridate; 4-(Pyren-1-yl)butyl Methylphosphonofluoridate; PBF; Pyrene-Butyl-Fluoridate; Methyl (4-(pyren-1-yl)butyl)phosphonofluoridate; [4-(1-Pyrenyl)butyl]methylphosphonofluoridate
EINECS	Contact for details

Quality Control

Our production of 4-(1-Pyrenyl)Butyl Methylphosphonofluoridate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.