Description

2-(3-Oxocyclopentyl)Acetyl Chloride is a reactive organic acid chloride intermediate characterized by its cyclopentanone and acyl chloride functional groups. This compound is valued for its role as a versatile building block in the synthesis of complex molecules, enabling the introduction of the 2-(3-oxocyclopentyl)acetyl moiety. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of prostaglandin analogs, steroid derivatives, and other bioactive molecules with cyclopentane rings.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structure contributes to specific biological activity.
• Fine Chemical Production: Serves as a precursor for fragrances, flavors, and specialty polymers requiring functionalized cyclopentane units.
• Academic & Industrial Research: Employed in methodological studies and the development of new synthetic routes involving ketone and acid chloride chemistry.
• Peptide Mimetics: The acyl chloride group is utilized for amide bond formation in the creation of constrained, non-peptidic scaffolds for drug discovery.

Basic Information

Product Name	2-(3-Oxocyclopentyl)Acetyl Chloride
CAS No.	66972-66-5
Molecular Formula	C7H9ClO2
Molecular Weight	160.60 g/mol
Synonyms	2-(3-Oxocyclopentyl)acetyl chloride; 3-Oxocyclopentaneacetic acid chloride; 2-(3-Oxocyclopentyl)ethanoyl chloride; (3-Oxocyclopentyl)acetyl chloride; 3-Oxocyclopentylacetyl chloride; Cyclopentanone-3-acetic acid chloride; 66972-66-5
EINECS	Contact for details

Quality Control

Our 2-(3-Oxocyclopentyl)Acetyl Chloride is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay, identity confirmation, and impurity profiling. Certificates of Analysis (COA) documenting purity (typically ≥95% by HPLC or GC), appearance, and other critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.