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4'-α-C-Allyl Uridine CAS NO 66723-28-2


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CAS No.:66723-28-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4'-α-C-Allyl Uridine is a modified nucleoside analog, a key building block in advanced pharmaceutical and biochemical research. This compound is valued for its role in the synthesis of novel oligonucleotides and prodrugs, enabling the development of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug discovery, nucleotide chemistry, and the development of modified RNA/DNA probes.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleotide analogs.
  • Biochemical Research: Used as a modified building block for studying RNA structure, function, and enzyme interactions.
  • Prodrug Development: Employed in creating lipophilic prodrugs to enhance the bioavailability of nucleoside-based therapeutics.
  • Antisense Oligonucleotide Synthesis: Serves as a specialty monomer for constructing oligonucleotides with tailored properties.
  • Diagnostic Probe Development: Utilized in the design of labeled nucleotides for diagnostic assays and imaging.

Basic Information

Product Name 4'-α-C-Allyl Uridine
CAS No. 66723-28-2
Molecular Formula C12H16N2O6
Molecular Weight 284.26 g/mol
Synonyms 4'-C-Allyluridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-(prop-2-en-1-yl)oxolan-2-yl)pyrimidine-2,4-dione; 4'-α-C-Allyluridine; Allyl Uridine Derivative; Modified Uridine; Nucleoside Analog C12H16N2O6
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Quality Control

Our 4'-α-C-Allyl Uridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.