Description

2''-Deoxy-2-o-Ethyluridine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a crucial building block and intermediate for the synthesis of novel antiviral and anticancer agents, particularly in the development of nucleotide-based therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleoside chemistry and prodrug design.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related pathways.
• Prodrug Development: Serves as a modified scaffold for creating prodrugs with enhanced bioavailability and targeted delivery.
• Antiviral Agent Synthesis: Building block for research into nucleoside reverse transcriptase inhibitors and other antiviral compounds.
• Labeled Compound Synthesis: Starting material for the preparation of isotopically labeled (e.g., C13, N15) nucleosides for metabolic tracing studies.
• Medicinal Chemistry: Core structure for structure-activity relationship (SAR) studies to optimize pharmacological properties.

Basic Information

Product Name	2''-Deoxy-2-o-Ethyluridine
CAS No.	66656-47-1
Molecular Formula	C11H16N2O6
Molecular Weight	272.25 g/mol
Synonyms	2'-Deoxy-2-O-ethyluridine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)-2-[(2-oxo-2,3-dihydropyrimidin-1-yl)methoxy]oxolan-3-yl]-3-ethyl-1,3-diazinane-2,4,6-trione; 2'-Deoxy-2'-O-ethyluridine; 2'-O-Ethyl-2'-deoxyuridine; 2'-O-Ethyluridine; Ethyluridine, 2'-deoxy-2'-O-
EINECS	Contact for details

Quality Control

Our 2''-Deoxy-2-o-Ethyluridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.