Description

Benzenepropanoyl Chloride, 4-Hydroxy- is a versatile aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functional groups, enabling efficient acylation reactions to introduce the 4-hydroxyphenylpropionyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or modifying agent for creating specialized polymers and liquid crystal materials.
• Peptide & Protein Research: Employed as an acylating agent in peptide coupling and protein modification studies.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and colorants.
• Flavor & Fragrance Industry: Used in the controlled synthesis of specific aromatic compounds.
• Academic & R&D Laboratories: A valuable reagent for methodological development and novel compound library synthesis.
• Material Science: For the surface functionalization of materials and creation of specialty coatings.

Basic Information

Product Name	Benzenepropanoyl Chloride, 4-Hydroxy-
CAS No.	66628-99-7
Molecular Formula	C9H9ClO2
Molecular Weight	184.62 g/mol
Synonyms	4-Hydroxybenzenepropanoyl Chloride; 3-(4-Hydroxyphenyl)propionyl Chloride; 4-Hydroxyphenylpropionyl Chloride; 3-(4-Hydroxyphenyl)propanoyl Chloride; (4-Hydroxyphenyl)propionic Acid Chloride; p-Hydroxyphenylpropionyl Chloride; p-Hydroxyhydrocinnamoyl Chloride; 66628-99-7
EINECS	Contact for details

Quality Control

Our Benzenepropanoyl Chloride, 4-Hydroxy- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.