Description

(2E,4E,6E,8E)-9-(3-Hydroxy-2,6,6-Trimethyl-1-Cyclohexenyl)-3,7-Dimethyl-Nona-2,4,6,8-Tetraenoic Acid is a high-purity, conjugated polyenoic acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a key synthetic intermediate for the development of novel retinoids and vitamin A analogs, which are crucial in dermatology and oncology applications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients with specific biological activity profiles.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel retinoid receptor agonists and antagonists for therapeutic development.
• Biochemical Research: Used as a reference standard or probe in studies of retinoic acid signaling pathways and cellular differentiation.
• Fine Chemical Synthesis: Acts as a versatile precursor for the preparation of complex polyene structures with potential applications in materials science.
• Agrochemical Development: Investigated as an intermediate for creating new plant growth regulators or bioactive compounds with specific modes of action.
• Cosmeceutical R&D: Explored for the development of next-generation anti-aging or skin-repair active ingredients that modulate skin cell behavior.

Basic Information

Product Name	(2E,4E,6E,8E)-9-(3-Hydroxy-2,6,6-Trimethyl-1-Cyclohexenyl)-3,7-Dimethyl-Nona-2,4,6,8-Tetraenoic Acid
CAS No.	66592-72-1
Molecular Formula	C20H28O3
Molecular Weight	316.44 g/mol
Synonyms	9-(3-Hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid; Arotinoid Acid; TTNN; (all-E)-Arotinoid Acid; Ro 13-7410 Acid; 3,7-Dimethyl-9-(3-hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
EINECS	Contact for details

Quality Control

Our (2E,4E,6E,8E)-9-(3-Hydroxy-2,6,6-Trimethyl-1-Cyclohexenyl)-3,7-Dimethyl-Nona-2,4,6,8-Tetraenoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectral data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C. The container should be kept in a cool, dry, and well-ventilated area, away from oxidizing agents. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.