Description

(2S,2'S)-3,4,4B,5,6,7,8,8Aβ,9,10-Decahydro-2',4Bα,8,8-Tetramethyl-1,4-Dioxospiro[Phenanthrene-2(1H),1'-Cyclopropane]-3β,7β,9α,10β-Tetrol 7-Acetate is a complex, high-purity spirocyclic diterpenoid derivative with significant potential in advanced organic synthesis and pharmaceutical research. This compound matters as a sophisticated chiral building block or a key intermediate for developing novel therapeutic agents, particularly in steroid and terpenoid chemistry. It is essential for research and development laboratories in the pharmaceutical, agrochemical, and fine chemical sectors seeking to explore new molecular entities with unique biological activities.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of novel steroid-mimetic drugs and bioactive terpenoids.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct intricate polycyclic frameworks due to its defined stereochemistry and functional groups.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop new compounds with potential anti-inflammatory, anti-cancer, or hormonal activity.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Investigated for its interaction with specific enzymes or receptors as part of mechanistic studies in biochemistry.
• Fine Chemical Production: Utilized in the pilot-scale manufacture of specialty chemicals and advanced materials requiring high stereochemical fidelity.

Basic Information

Item	Details
Product Name	(2S,2'S)-3,4,4B,5,6,7,8,8Aβ,9,10-Decahydro-2',4Bα,8,8-Tetramethyl-1,4-Dioxospiro[Phenanthrene-2(1H),1'-Cyclopropane]-3β,7β,9α,10β-Tetrol 7-Acetate
CAS No.	66584-98-3
Molecular Formula	C23H32O7
Molecular Weight	420.50 g/mol
Synonyms	7-Acetoxy-3,4,4b,5,6,7,8,8aβ,9,10-decahydro-2',4bα,8,8-tetramethyl-1,4-dioxospiro[phenanthrene-2(1H),1'-cyclopropane]-3β,7β,9α,10β-tetrol; 7β-Acetoxy-3β,7β,9α,10β-tetrahydroxy-2',4bα,8,8-tetramethyl-1,4-dioxospiro[cyclopropane-1,2'(1'H)-phenanthrene]; Spirocyclopropane-diterpenoid acetate; CAS 66584-98-3; 7-Acetate derivative of the corresponding tetrol spiro compound.
EINECS	Contact for details

Quality Control

Our (2S,2'S)-3,4,4B,5,6,7,8,8Aβ,9,10-Decahydro-2',4Bα,8,8-Tetramethyl-1,4-Dioxospiro[Phenanthrene-2(1H),1'-Cyclopropane]-3β,7β,9α,10β-Tetrol 7-Acetate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR, and MS for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.