Description

Bis(T-Butyldimethylsiloxy)Ethane is a specialized organosilicon compound, widely recognized as a versatile silylating agent and protecting group reagent in advanced organic synthesis. Its core value lies in its ability to selectively protect hydroxyl groups, offering superior stability under a range of reaction conditions compared to simpler silyl ethers. This makes it an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, where precise molecular construction is critical.

Application

• As a protecting group reagent for diols and polyols in multi-step pharmaceutical synthesis.
• Key intermediate in the production of nucleoside analogs and other active pharmaceutical ingredients (APIs).
• Used in the synthesis of complex natural products and fine chemicals requiring selective hydroxyl protection.
• Employed as a silylating agent in the derivatization of compounds for gas chromatography (GC) analysis.
• Building block for the preparation of specialty silicone polymers and functional materials.
• Reagent in agrochemical research for the development of novel active ingredients.

Basic Information

Product Name	Bis(T-Butyldimethylsiloxy)Ethane
CAS No.	66548-22-9
Molecular Formula	C14H34O2Si2
Molecular Weight	290.60 g/mol
Synonyms	1,2-Bis(tert-butyldimethylsiloxy)ethane; Ethane-1,2-diyl bis(tert-butyldimethylsilyl) ether; 1,2-Bis[(1,1-dimethylethyl)dimethylsilyl]oxy]ethane; 1,2-Bis-O-(tert-butyldimethylsilyl)ethane; BTO; BTDMS-ethane; tert-Butyldimethylsilyl ether of ethylene glycol
EINECS	Contact for details

Quality Control

Our Bis(T-Butyldimethylsiloxy)Ethane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.