Description

21-Hydroxy-20-Methyl-Pregn-4-Ene-3-One is a high-purity steroid intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters for its role as a key building block in the production of specialized corticosteroid and progestogen APIs, where structural precision is critical. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical and fine chemical industries for developing novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of advanced corticosteroid and progestogen active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for pharmacological studies and the development of new steroid-based therapeutics.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized steroid derivatives.

Basic Information

Product Name	21-Hydroxy-20-Methyl-Pregn-4-Ene-3-One
CAS No.	66512-11-6
Molecular Formula	C22H34O2
Molecular Weight	330.51 g/mol
Synonyms	20-Methyl-21-hydroxypregn-4-ene-3-one; 20-Methyl-21-hydroxy-4-pregnene-3-one; 21-Hydroxy-20-methyl-4-pregnene-3-one; 20-Methyl-21-hydroxypregn-4-en-3-one; Pregn-4-ene-3-one, 21-hydroxy-20-methyl-; (20R)-21-Hydroxy-20-methylpregn-4-en-3-one
EINECS	Contact for details

Quality Control

Our 21-Hydroxy-20-Methyl-Pregn-4-Ene-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.