Description

Diethyl 3-Bromo-1-Propene Phosphonate is a specialized organophosphorus compound that serves as a valuable building block in advanced organic synthesis. Its core value lies in its ability to act as a key reagent in the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient and stereoselective construction of carbon-carbon double bonds. This makes it an essential material for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for complex molecule assembly.

Application

• Pharmaceutical Intermediate: A critical reagent for synthesizing α,β-unsaturated esters, ketones, and nitriles, which are key scaffolds in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and pesticides that require specific alkene geometries.
• Fine Chemical Manufacturing: Employed in the synthesis of flavors, fragrances, and specialty materials where precise olefination is required.
• Material Science Research: Acts as a precursor for functionalized alkenes used in polymer modification and the development of novel organic materials.
• Academic & R&D Laboratories: A staple reagent for methodology development and complex natural product synthesis in research settings.

Basic Information

Product Name	Diethyl 3-Bromo-1-Propene Phosphonate
CAS No.	66498-59-7
Molecular Formula	C7H14BrO3P
Molecular Weight	257.06 g/mol
Synonyms	Diethyl (3-Bromoprop-2-en-1-yl)phosphonate; (3-Bromoallyl)phosphonic Acid Diethyl Ester; 3-Bromoallylphosphonic Acid Diethyl Ester; Diethyl (3-Bromoallyl)phosphonate; Diethyl 3-Bromoallylphosphonate; (E/Z)-Diethyl 3-bromoallylphosphonate; Phosphonic acid, P-(3-bromo-2-propen-1-yl)-, diethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl 3-Bromo-1-Propene Phosphonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed in a dry and inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.