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5'-Uridylic Acid, 5-Bromo-, Monosodium Salt CAS NO 66487-07-8


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CAS No.:66487-07-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5'-Uridylic Acid, 5-Bromo-, Monosodium Salt is a modified nucleotide monophosphate of significant research and industrial interest. This compound serves as a crucial building block and biochemical tool due to its halogenated base structure. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and nucleic acid chemistry. The product is supplied with a focus on high purity and consistency to meet stringent application requirements.

Application

  • Pharmaceutical Intermediate: Used in the research and synthesis of novel nucleoside-based antiviral or anticancer agents.
  • Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies, particularly those involving kinases, polymerases, or other nucleotide-processing enzymes.
  • Oligonucleotide Synthesis: Serves as a modified monomer for the solid-phase synthesis of labeled or functionally altered DNA/RNA probes.
  • Diagnostic Reagent Development: Employed in the creation of specialized assays and detection systems that require nucleotide analogs.
  • Enzyme Mechanism Studies: Utilized to investigate the structure-activity relationships and catalytic mechanisms of nucleic acid-metabolizing enzymes.
  • Reference Standard: Provides a high-purity standard for analytical method development and quality control in related chemical production.

Basic Information

Product Name 5'-Uridylic Acid, 5-Bromo-, Monosodium Salt
CAS No. 66487-07-8
Molecular Formula C9H11BrN2NaO9P
Molecular Weight 449.06 g/mol
Synonyms 5-Bromouridine 5'-monophosphate monosodium salt; 5-Br-UMP sodium salt; 5-Bromouridylic acid sodium salt; Sodium 5-bromouridine 5'-monophosphate; 5-Bromo-UMP Na; 5-Bromouridine 5'-(dihydrogen phosphate) monosodium salt; BrdUMP sodium salt
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Quality Control

Our 5'-Uridylic Acid, 5-Bromo-, Monosodium Salt is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with key parameters including assay, impurity profile, and residual solvent content. Our quality commitment supports applications in GMP-compatible research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 5.0%
Heavy Metals ≤ 20 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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