Description

1,3-Benzodioxole-4-Carbonyl Chloride (9Ci) is a versatile and highly reactive organic intermediate, primarily used as a key building block in the synthesis of complex molecules. Its value lies in its ability to efficiently introduce the 1,3-benzodioxole moiety, a privileged scaffold found in numerous bioactive compounds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing the benzodioxole structural motif, which is associated with various pharmacological activities.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the benzodioxole group can enhance biological activity and stability.
• Fine Chemical Manufacturing: Serves as a building block for creating complex dyes, pigments, and specialty chemicals requiring specific functionalization.
• Material Science Research: Employed in the development of novel polymers and organic electronic materials where its reactive acid chloride group allows for polymerization or functional group attachment.
• Ligand and Catalyst Development: Useful for synthesizing specialized ligands for metal catalysis or as a precursor for creating catalyst frameworks in organic synthesis.

Basic Information

Product Name	1,3-Benzodioxole-4-Carbonyl Chloride (9Ci)
CAS No.	66411-55-0
Molecular Formula	C8H5ClO3
Molecular Weight	184.58 g/mol
Synonyms	4-Piperonyloyl Chloride; 1,3-Benzodioxole-4-carboxylic acid chloride; Piperonyloyl Chloride; 3,4-(Methylenedioxy)benzoyl Chloride; 3,4-Methylenedioxybenzoyl Chloride; 1,3-Benzodioxol-4-ylcarbonyl Chloride; 4-Carboxypiperonyl Chloride
EINECS	Contact for details

Quality Control

Our 1,3-Benzodioxole-4-Carbonyl Chloride (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.