Description

Ranitidine is a histamine H₂-receptor antagonist that effectively inhibits gastric acid secretion. This makes it a critical active pharmaceutical ingredient (API) for the formulation of medications targeting acid-related gastrointestinal disorders. It is essential for pharmaceutical manufacturers producing treatments for conditions such as peptic ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. Our supply of high-purity Ranitidine CAS NO 66357-35-5 ensures reliability and consistency for global pharmaceutical production.

Application

The primary and derived applications for Ranitidine include:

• Pharmaceutical API: Core active ingredient in prescription and over-the-counter anti-ulcer and antacid medications.
• Tablet Formulation: Used in the manufacture of solid oral dosage forms, including standard and effervescent tablets.
• Capsule Production: Incorporated into hard gelatin or vegetarian capsules for oral delivery.
• Syrup & Oral Solution: Suitable for formulating liquid dosage forms for pediatric or geriatric patients.
• Veterinary Pharmaceuticals: Applied in veterinary medicine for treating gastric ulcers in animals.
• Research & Development: Serves as a reference standard and key intermediate in pharmacological research.

Basic Information

Product Name	Ranitidine
CAS No.	66357-35-5
Molecular Formula	C13H22N4O3S
Molecular Weight	314.40 g/mol
Synonyms	Ranitidine Hydrochloride (common salt form); Zantac (trade name); AH-19065; N-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine; 1,1-Ethenediamine, N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-; Ranitidin; Ranitidina; Ranitidinum.
EINECS	Contact for details

Quality Control

Our Ranitidine is manufactured and tested under strict quality management systems. We ensure compliance with major pharmacopoeial standards, including USP, EP, and BP monographs. Every batch undergoes rigorous analytical testing for identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA), detailing all test results against specifications, is provided with each shipment to guarantee traceability and quality assurance for our B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Microbial Limits	Meets USP/EP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.