Description

3'-Azido-2'-3'-Dideoxyguanosine is a chemically modified nucleoside analog, a key building block in medicinal chemistry and life science research. This compound is valued for its role as a versatile intermediate in the synthesis of novel antiviral agents and nucleotide-based therapeutics. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors for drug discovery and development programs.

Application

• Antiviral Drug Research: Serves as a critical synthetic intermediate in the development of nucleoside reverse transcriptase inhibitors (NRTIs) and other antiviral compounds.
• Medicinal Chemistry: Used as a specialized building block for the synthesis of modified nucleotides and oligonucleotides with potential therapeutic activity.
• Biochemical Research: Employed in studies investigating DNA/RNA metabolism, enzyme mechanisms, and the biochemical pathways of nucleotide analogs.
• Probe Development: Can be utilized to create labeled or tagged nucleotide probes for diagnostic assays and molecular biology applications.
• Pharmaceutical Intermediates: Acts as a high-value precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) targeting viral infections.

Basic Information

Product Name	3'-Azido-2'-3'-Dideoxyguanosine
CAS No.	66323-46-4
Molecular Formula	C10H11N9O3
Molecular Weight	305.26 g/mol
Synonyms	3'-Azido-2',3'-dideoxyguanosine; 3'-Azido-ddG; AZT-Guanosine analog; 9-[(2R,5S)-5-(Azidomethyl)oxolan-2-yl]-1,9-dihydro-6H-purin-6-one; 2',3'-Dideoxy-3'-azidoguanosine; N3-ddG; Azidodideoxyguanosine
EINECS	Contact for details

Quality Control

Our 3'-Azido-2'-3'-Dideoxyguanosine is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical characterization, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.