Description

4-Thiomorpholinecarbonyl Chloride, 3-Oxo- (9Ci) is a reactive heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized thiomorpholine scaffold, enabling the introduction of the 3-oxo-thiomorpholine-4-carbonyl moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting the central nervous system (CNS) or possessing enzyme-inhibitory activity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, or insecticides that incorporate the thiomorpholine heterocycle.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling or modifying biomolecules, useful in probe and linker synthesis for studying biological systems.
• Material Science Research: Employed in the creation of novel polymers or functional materials where the incorporation of sulfur and nitrogen heterocycles can impart specific properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses producing bespoke intermediates for client R&D projects.

Basic Information

Product Name	4-Thiomorpholinecarbonyl Chloride, 3-Oxo- (9Ci)
CAS No.	66313-53-9
Molecular Formula	C5H6ClNO2S
Molecular Weight	179.62 g/mol
Synonyms	3-Oxothiomorpholine-4-carbonyl chloride; 4-Chlorocarbonyl-3-oxothiomorpholine; Thiomorpholine-4-carbonyl chloride, 3-oxo-; 3-Oxo-thiomorpholine-4-carboxylic acid chloride; 1,1-Dioxo-1,4-thiazinane-4-carbonyl chloride; 1,1-Dioxo-1λ⁶,4-thiazinane-4-carbonyl chloride; 3-Oxo-1,1-dioxo-1,4-thiazinane-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Thiomorpholinecarbonyl Chloride, 3-Oxo- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.