Description

3-Oxazolidinecarbonyl Chloride, 2-Oxo- (9Ci) is a reactive acyl chloride derivative of an oxazolidinone, serving as a versatile and high-value building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 2-oxo-oxazolidinecarbonyl moiety, a key structural motif for modulating biological activity and material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials. Its precise reactivity profile makes it a critical intermediate for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antibiotics, particularly oxazolidinone-class antibacterial agents.
• Agrochemical Synthesis: Used in creating advanced fungicides and herbicides with specific mode-of-action targets.
• Peptide Mimetics & PROTACs: Facilitates the construction of peptide-like structures and proteolysis-targeting chimeras (PROTACs) for drug discovery.
• Polymer Modification: Acts as a functional monomer or grafting agent to introduce heterocyclic functionalities into polymer backbones.
• Material Science Research: Employed in developing novel organic frameworks, coatings, and specialty materials with tailored properties.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules to study biological pathways and interactions.

Basic Information

Product Name	3-Oxazolidinecarbonyl Chloride, 2-Oxo- (9Ci)
CAS No.	66313-48-2
Molecular Formula	C4H4ClNO3
Molecular Weight	149.53 g/mol
Synonyms	2-Oxooxazolidine-3-carbonyl chloride; 3-Carbamoyloxazolidin-2-one chloride; Oxazolidin-2-one-3-carbonyl chloride; 2-Oxo-3-oxazolidinecarbonyl chloride; 3-Oxazolidinecarbonyl chloride, 2-oxo-; 2-Oxazolidinone-3-carbonyl chloride; (2-Oxo-1,3-oxazolidin-3-yl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Oxazolidinecarbonyl Chloride, 2-Oxo- (9Ci) is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting research and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided to guarantee batch-to-batch consistency and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Titration)	95.0 - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.