Description

19-Iodocholesterol 3-Methyl Ether is a chemically modified sterol derivative, specifically an iodinated cholesterol analog. This compound is a valuable synthetic intermediate and research tool, particularly valued for its iodine atom which can serve as a radiolabeling site or a handle for further chemical transformations. It is primarily utilized by researchers and manufacturers in the pharmaceutical, life sciences, and specialty chemical sectors for applications in steroid chemistry, radiopharmaceutical precursor synthesis, and biochemical studies.

Application

• Pharmaceutical Research & Development: As a key synthetic intermediate in the preparation of novel steroid-based drug candidates and radiopharmaceuticals.
• Biochemical Probes: Used in the study of cholesterol metabolism, membrane biology, and protein-sterol interactions due to its modified cholesterol structure.
• Radiolabeling Precursor: The iodine atom provides a site for radioiodination (e.g., with I-125 or I-131) to create tracers for imaging or metabolic studies.
• Organic Synthesis Building Block: Employed in steroid chemistry to introduce functional groups or create more complex steroidal architectures.
• Reference Standard: Serves as an analytical standard in quality control and method development for laboratories analyzing sterol compounds.

Basic Information

Product Name	19-Iodocholesterol 3-Methyl Ether
CAS No.	66277-11-0
Molecular Formula	C28H47IO
Molecular Weight	526.58 g/mol
Synonyms	19-Iodo-5-cholesten-3β-ol 3-methyl ether; 3β-Methoxy-19-iodocholest-5-ene; 19-Iodocholest-5-en-3β-ol methyl ether; Cholest-5-en-3β-ol, 19-iodo-, 3-methyl ether; 19-Iodo-3-methoxycholest-5-ene
EINECS	Contact for details

Quality Control

Our 19-Iodocholesterol 3-Methyl Ether is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.