Description

2,2,2-Trichloro-1,1-dimethylethyl chloroformate is a specialized, highly reactive chloroformate ester used as a versatile reagent in organic synthesis. Its primary value lies in its role as a protecting group agent and an intermediate for the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and process development scientists in fine chemical, active pharmaceutical ingredient (API), and advanced material manufacturing who require high-purity, reliable building blocks.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for introducing specific functional groups.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where its reactive chloroformate group is utilized.
• Peptide Chemistry: Acts as a reagent for the temporary protection of amino groups during solid-phase and solution-phase peptide synthesis.
• Polymer Science: Serves as a monomer or chain modifier in the synthesis of specialty polymers, such as polycarbonates and polyurethanes, with specific properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs as a versatile reagent for constructing complex molecular architectures and novel compounds.
• Dye & Pigment Manufacturing: Used as an intermediate in the synthesis of certain high-performance dyes and organic pigments.

Basic Information

Product Name	2,2,2-Trichloro-1,1-dimethylethyl Chloroformate
CAS No.	66270-36-8
Molecular Formula	C7H10Cl4O2
Molecular Weight	260.96 g/mol
Synonyms	2,2,2-Trichloro-tert-butyl Chloroformate; Trichloro-tert-butyl Chloroformate; (2,2,2-Trichloro-1,1-dimethylethoxy)carbonyl Chloride; 1,1-Dimethyl-2,2,2-trichloroethyl Chloroformate; TCBOC-Cl; Trichloro-tert-butoxycarbonyl Chloride; Troc-Cl; 2,2,2-Trichloro-1,1-dimethylethyl Carbonochloridate
EINECS	Contact for details

Quality Control

Our 2,2,2-Trichloro-1,1-dimethylethyl chloroformate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.45 g/cm³
Refractive Index (n20D)	~1.460

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.