Description

2-Bromoisovaleryl Chloride is a versatile and highly reactive organic acid chloride derivative, primarily used as a key building block in advanced chemical synthesis. Its value lies in its ability to efficiently introduce the 2-bromoisovaleryl moiety, a crucial functional group for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Polymer Chemistry: Used as an initiator or functional monomer in controlled radical polymerization techniques, such as Atom Transfer Radical Polymerization (ATRP).
• Agrochemical Synthesis: Serves as a key building block for creating novel herbicides, fungicides, and plant growth regulators.
• Peptide & Protein Modification: Employed for site-specific labeling or functionalization of biomolecules in biochemical research.
• Material Science: Used in the production of specialty polymers, coatings, and advanced materials with tailored properties.
• Organic Synthesis: A versatile acylating agent for introducing the bromoisovaleryl group in multi-step synthetic routes for fine chemicals.

Basic Information

Product Name	2-Bromoisovaleryl Chloride
CAS No.	66067-58-1
Molecular Formula	C5H8BrClO
Molecular Weight	199.47 g/mol
Synonyms	2-Bromo-3-methylbutanoyl Chloride; 2-Bromoisovaleryl Chloride; 2-Bromo-3-methylbutyryl Chloride; α-Bromoisovaleryl Chloride; 2-Bromo-3-methylbutanoic Acid Chloride; Isobutyl Bromoacetyl Chloride; 2-Bromo-3-methylbutanoyl Chloride; 2-Bromoisovaleroyl Chloride
EINECS	Contact for details

Quality Control

Our 2-Bromoisovaleryl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We adhere to current Good Manufacturing Practices (cGMP) where applicable. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically verified by techniques such as GC, HPLC, and NMR. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.